Application

Anti-SHANK1a Antibody, N-terminus is an antibody against SHANK1a for use in WB.

Research CategoryNeuroscience

Western blotting: 1:500-1:1,000

Optimal working dilutions must be determined by the end user.

Research Sub CategorySynapse & Synaptic Biology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PDS-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Immunogen

Synthetic peptide corresponding to the N-terminus of rat Shank1a.

Epitope: N-terminus

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Format: Purified

Specificity

Recognizes Shank1a, N-terminal.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.